Antônio Austregésilo Martins, Bruno Rocha da Silva, Marcelo Victor Sidou Lemos, Carla Kuroki Kawamoto Pereira, Sérgio Luís da Silva Pereira
Objective: The aim of this study was to conduct an integrative literature review on the effectiveness of the use of pomegranate-based products (Punica granatum) in periodontitis. Material and Methods: The collection of randomized clinical studies in humans was performed in March and August 2021 in the PubMed, Lilacs and Scielo databases, crossing the following descriptors available in the Decs: “pomegranate”, “periodontitis” and “treatment”. Results: After excluding publications in the thesis format, dissertation, book chapter, in vitro articles and those that were not related to the research theme, 2 studies were selected for full reading that were in accordance with the eligibility criteria of the present study. Conclusion: Within the limits of this study, the present integrative review evaluated that pomegranate-based products have therapeutic potential as an adjunct in the treatment of periodontitis, but more long-term clinical studies with similar methodological characteristics are still necessary to establish the effectiveness of pomegranate in the treatment of periodontitis.
Martins AA, da Silva BR, Lemos MVS, Pereira CKK, Pereira SLS. Pomegranate (Punica granatum) as an adjunct in the treatment of periodontitis: An integrative literature review. Braz J Periodontol. 2023 Jan-Mar;33(1):76-86.